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Work in collaboration with excellence
Tailoring every study to your specific project needs, we provide a unique blend of pre-validated disease models, alongside bespoke model development services. We work in a flexible, transparent way and pride ourselves on the collaborative working relationships we have built with our clients.
All studies are supported by dedicated project leaders and, as our highly qualified in vivo pharmacology experts sit within integrated drug discovery teams, we are able to maximise multidisciplinary study support and, ultimately, accelerate your drug discovery efforts.
Our experts specialise in four key therapeutic areas:
In Vivo Pharmacology
Demonstrating in vivo efficacy of novel therapeutics is a pivotal phase in any drug discovery programme. As specialists in vivo pharmacology, we understand what it takes to design and perform robust experimental animal models that will progress your compounds towards the clinic.
We offer flexible working arrangements, including standalone fee-for-service options, as well as FTE-based project arrangements.
Sygnature Discovery - Enabling Success
CNS disorders
Extensive expertise including psychedelic testing, microdialysis and psychiatric disorders in this challenging field for drug development.
Kidney disorders
Our acute and chronic models of kidney disease with clinically relevant endpoints offer a reliable platform for therapeutic validation across different modalities.
Metabolic Disorders
From insulin resistance to diabetic complications, we’ve a strong track record of performing high-quality in vivo pharmacology investigations in the growing metabolic space.
Oncology
The team will work in close collaboration with you to support, design and deliver bespoke in vivo pharmacology studies tailored to your specific needs.
Animal welfare is our top priority at Sygnature Discovery. We employ the highest standards of animal care and implement the principles of the 3Rs (replacement, reduction and refinement) to all studies, and have worked hard to foster a culture of compassion and care towards all our animals.
A history of innovation
Sygnature Discovery has been offering high-quality drug discovery services since 2004, providing clients with guidance and support fin the development of novel medicines.
More than 80% of our scientists hold a PhD, and many have considerable experience of drug discovery in the pharmaceutical industry. Experience which is applied to every research project we undertake.